* FTSEurofirst 300 falls 2.5 pct to 949.52
* Focus returns to economy after Obama election victory
* Phamaceuticals, oils lead decline
By Rebekah Curtis
LONDON, Nov 5 (Reuters) - European stocks lost 2.5 percent early on Wednesday, breaking six straight days of gains as oil and pharmaceutical shares fell and investor focus returned to the economy after Barack Obama's election as U.S. president.
At 0949 GMT the pan-European FTSEurofirst 300 index was 2.5 percent lower 949.52. European stocks ended the previous session up 4.3 percent at 974.15 points, hitting a one-month closing high.
Analysts said that an Obama win had been largely priced in after six days of gains for European shares.
The index has lost 37 percent so far this year. The new Obama administration, which takes office in January, will face the world's worst financial crisis since the Great Depression, and a potentially steep downturn in the global economy.
"He (Obama) has no easy job," said Heinz-Gerd Sonnenschein, equity strategist at Postbank in Bonn, Germany. "Today we are looking at what may come from the economic side...A lot of problems are ahead with the housing market in the U.S. and with the global economy cooling too," he added.
"Volatility may cool a little bit but for the whole market I see...more potential on the downside."
Pharmaceuticals were the heaviest drag on the index, shedding their recent gains. GlaxoSmithKline <GSK.L> lost 4.9 percent, Novartis <NOVN.VX> dropped 4.3 percent and Roche <ROG.VX> went down 3.7 percent.
Among oil shares, BP <BP.L>, Royal Dutch Shell <RDSa.L> and Total <TOTF.PA> all dropped about 3 percent as crude fell nearly 4 percent to below $68 a barrel. Shell traded ex-dividend on Wednesday, adding to the downward pressure on that stock.
Around Europe, Britain's FTSE 100 <
> lost 2.6 percent, Germany's DAX < > shed 2 percent and France's CAC < > lost 2.7 percent.In Asia, Japan's Nikkei rose 4.5 percent. Major U.S. stock indexes rose between about 3 and 4 percent with the biggest Election Day rally ever on Tuesday as a backdrop.
BOE, ECB EYED
Investor attention in Europe turned to the European Central Bank and the Bank of England, which are both widely expected to slash borrowing costs on Thursday, following a recent string of rate cuts from policy-makers around the world.
The BoE and ECB are both expected to cut rates by at least half a percentage point, Reuters polls showed.
Banks stocks also fell on Wednesday. BNP Paribas shed 3.3 percent after saying its third-quarter net profit more than halved due to higher provisions tied to the financial crisis.
HSBC <HSBA.L> lost 1.7 percent and BBVA <BBVA.M> was 1.9 percent lower.
Shares in Allied Irish Banks <ALBK.I> tumbled 8 percent after it cut its full-year earnings forecast, increased its bad debt charge expectations and cancelled its 2008 cash dividend to raise capital ratios.
But recently battered shares in Royal Bank of Scotland <RBS.L> rose 3.2 percent.
The world's largest steelmaker ArcelorMittal <ISPA.AS> dived 13.5 percent after it forecast weaker fourth-quarter earnings, cut production further and put its growth plans on hold in the face of a global economic slowdown.
Miners also dragged on the index, with Vedanta Resources <VED.L>, Kazakhmys <KAZ.L> and Rio Tinto <RIO.L> shedding between 8.2 and 10.2 percent. (Editing by Chris Wickham)